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Leucettamine B
CAS No. 147395-96-8
Leucettamine B( —— )
Catalog No. M12028 CAS No. 147395-96-8
Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameLeucettamine B
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NoteResearch use only, not for human use.
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Brief DescriptionLeucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
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DescriptionLeucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetCLK
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RecptorCLK
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Research Area——
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Indication——
Chemical Information
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CAS Number147395-96-8
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Formula Weight245.238
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Molecular FormulaC12H11N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(5Z)-2-amino-5-(1,3-benzodioxol-5-ylmethylidene)-3-methylimidazol-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chan GW, et al. J Nat Prod. 1993 Jan;56(1):116-21.
2. Debdab M, et al. J Med Chem. 2011 Jun 23;54(12):4172-86.
3. Tahtouh T, et al. J Med Chem. 2012 Nov 8;55(21):9312-30.
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