Cart
sales@molnova.com
Leucettamine B
CAS No. 147395-96-8
Leucettamine B ( —— )
Catalog No. M12028 CAS No. 147395-96-8
Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameLeucettamine B
-
NoteResearch use only, not for human use.
-
Brief DescriptionLeucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
-
DescriptionLeucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetCLK
-
RecptorCLK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number147395-96-8
-
Formula Weight245.24
-
Molecular FormulaC12H11N3O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name(5Z)-2-amino-5-(1,3-benzodioxol-5-ylmethylidene)-3-methylimidazol-4-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Chan GW, et al. J Nat Prod. 1993 Jan;56(1):116-21.
2. Debdab M, et al. J Med Chem. 2011 Jun 23;54(12):4172-86.
3. Tahtouh T, et al. J Med Chem. 2012 Nov 8;55(21):9312-30.
2. Debdab M, et al. J Med Chem. 2011 Jun 23;54(12):4172-86.
3. Tahtouh T, et al. J Med Chem. 2012 Nov 8;55(21):9312-30.
molnova catalog
related products
-
KuWal151
KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.
-
CLK inhibitor T3
CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110nM for CLK1,2 and 3, respectively.
-
SRI-29329
A potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and4, respectively; shows no significant activity for CLK3, CDK1, CDK4 and CDK6 (IC50>1,000 nM).
